From Eli Lilly abandoning evacetrapib in the final stages of trials to the surprising placebo effect, this week’s Research Ethics Roundup shines the spotlight on clinical trials that could shape the future of research.
Gene Editing Record Smashed in Pigs: A team from Harvard Medical School, led by geneticist George Church, has used CRISPR technology to modify more than 20 genes in pig embryo and deactivate more than 60 viruses that could cause disease in human [...] Read more
Two recent studies have generated debate within the research community. We explore those studies, as well as other recent stories about research in the popular media, in this week’s Research Ethics Roundup.
Has US Biomedical Research on Chimpanzees Come to an End?: In June, the US Fish and Wildlife Service announced its plans to classify captive chimpanzees, including those used for research purposes, as endangered animals under the Endangered Species Act. In this article for Science, David Grimm explores the effect of that decision.
In this week’s Research Ethics Roundup, we explore how shifting conceptions of research—from the growing demand for the sharing of clinical trial data to a renewed emphasis on statistical power in animal research—are challenging current thinking. Read on and share your thoughts on these pieces and other research ethics and oversight news in the comments.
Is the Placebo Effect in Some People’s Genes?: A recent study published in Trends in Molecular Biology found that an individual’s response to a placebo may be affected by his or her genetics. This article from Reuters provides an [...] Read more
by Jim Gearhart, BA, Member of the Board of Directors for Quorum Review IRB
If you attended PRIM&R's 2014 Advancing Ethical Research (AER14) Conference in December, there's a good chance you attended the performance of "The Drama of DNA: Implications of Genomic Protocols that Reconceptualize the Boundaries of 'Normalcy.'" I'm saying the chances were good because the venue for "The Drama of DNA" was a large conference room filled to standing-room only capacity. In the time since the AER14, I have recalled more than once the themes that "The Drama of DNA" shared with us.
The "Drama of DNA" sprang from the [...] Read more
By Kathy Banks, BSc, MSc, continuing review coordinator, animal ethics, University of British Columbia
PRIM&R is pleased to share a post from Kathy Banks, a member of the PRIM&R Blog Squad for the 2015 Institutional Animal Care and Use Committee (IACUC) Conference. The PRIM&R Blog Squad is composed of PRIM&R members who blog here, on Ampersand, to give our readers an inside peek of what happened at the conference in Boston, MA.
Gene therapy! We can cure ALL the diseases! More [...] Read more