The research ethics community mourns the loss of Charles R. McCarthy, PhD, a giant of the research ethics field and a beloved member of the PRIM&R family, who passed away on October 14, 2022, at the age of 96. ”Charlie,” as he was known to all who were lucky enough to know and work with him, served on the PRIM&R Board of Directors from 1993 to 2011. He was awarded PRIM&R’s Lifetime Achievement Award for Excellence in Research Ethics in 2003, became a Distinguished Leader of PRIM&R in 2012, and was recognized as a Pillar of PRIM&R in 2021.   Charlie was a true founding father of the field of human research protections. While at the NIH in the early 1970s, Charlie helped to draft the National Research Act for the US Congress. Enacted in 1974, the National Research Act created the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and required that Department of Health Education and Welfare (DHEW) create human subjects protection regulations. Charlie served as the DHEW liaison to the National Commission, which went on to create the Belmont Report, and drafted for DHEW the first set of regulations for the protection of human subjects of research.  Read more