In this week’s Research Ethics Roundup, the 3Rs, bias in research, and compensation for research participants serve as food for thought.

What does the increase in numbers of animals used in research mean?: Statistics indicating that the use of animals in scientific research in the United Kingdom (UK) increased in 2011 were recently released. While some are concerned that this trend may indicate deviation from the 3Rs –reduction, refinement, and replacement– others believe the implications of these statistics may be more benign.