TAG ARCHIVES FOR Translatability

4
Feb2020

Women are two-thirds of the world’s blind population, and there is no clear evidence for the cause of this alarming statistic. Dr. Janine Austin Clayton’s keynote address, "It’s About Quality Construction—Advancing a Foundational Framework for Rigorous Research Relevant to the Health of Women," at AER19 began with this disturbing fact as she described her path from being an ophthalmologist to the Director for NIH’s Office of Research on Women’s Health (ORWH). As she discussed this, and other startling statistics regarding women’s health in the United States, it caused me to wonder why gender and sex are not routinely considered in study design. How are studies ensuring that women (and sex as a biological variable) are integrated into the design of animal and human research studies so that knowledge and treatments gained from these studies can be generalizable and effective for both men and women? Read more

21
Apr2017

This week’s Research Ethics Roundup examines the New England Journal of Medicine’s (NEJM) editor-in-chief’s call for a new approach to sharing clinical trial data, how experts are trying to improve drug testing success rates by reviewing pre-clinical research assumptions, a National Academies committee’s call for a nongovernmental body to promote research integrity, and a new study that rebuts critics’ claims that the Food and Drug Administration (FDA) is slow to approve new drugs for the American market. Read more

13
Mar2017

The first of three distinguished speakers at PRIM&R's 2017 IACUC Conference is Craig L. Franklin, DVM, PhD, DACLAM, professor of veterinary pathobiology at the University of Missouri. In addition to his professorship, Dr. Franklin directs the Mutant Mouse Resource and Research Center, a National Institutes of Health-funded repository of genetically engineered mutant mice; the Comparative Medicine Program, a post-DVM laboratory animal medicine residency and advanced degree program; and the Veterinary Research Scholars Program, a summer research program for veterinary students. He is also an associate director of the University of Missouri Metagenomics Laboratory and is a co-investigator for the Rat Resource and Research Center. Read more

10
Mar2017

This week’s Research Ethics Roundup covers experts’ views on the future of informed consent, why neuroscientists are not studying animals’ natural behavior, Food and Drug Administration (FDA)’s defenders highlight its success record, and Nature reacts to a science journalism infographic. Read more