The review criteria utilized by IRBs possess an inherent flexibility that has allowed them to adapt to a wide range of research over the past several decades Over that time span, many questions have arisen as to whether the IRB regulations can adequately apply to such innovations as organ transplants, Car-T cell therapies, and research using digital technology.  In the face of such rapid change, in all cases, however, we have seen the wisdom of those who drafted the regulations vindicated, as the IRB review criteria have continued to protect participants in all types, styles, and manner of research. Read more